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Frontiers in Comparative Medicine

Frontiers in Comparative Medicine

Foreword by ROBERT A. GOOD
Copyright Date: 1972
Edition: NED - New edition
Pages: 104
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  • Book Info
    Frontiers in Comparative Medicine
    Book Description:

    Frontiers in Comparative Medicine was first published in 1972. In this initial volume of the series to be based on the Wesley W. Spink Lectures on Comparative Medicine, Dr. Beveridge, the noted British scientist, discusses the contributions to human medicine resulting from studies of disease in animals. The book serves as an excellent introduction to this important aspect of science, suitable for general readers as well as for those studying or working in the medical, biological, or social sciences. Dr. Beveridge examines the methodology of comparative science and tells of the remarkable series of key discoveries of disease agents which have emerged from research on animals. He explains the reasons for the success of animal studies in connection with human disease and makes a strong case for more research on naturally occurring animal models. The author describes current comparative studies in cancer, cardiovascular diseases, neuropathology, immunopathology, congenial defects, metal health, reproduction, and population regulation. He shows that in each of these subjects results that have far-reaching implications for human welfare and medicine are being obtained. In the final section he assembles the available evidence about the origin of human influenza pandemics. He points to a conclusion that they probably result from a hybridization of human and animal strains of the disease agent and that the usual place where this occurs appears to be the plains of Central Asia. He emphasizes the need for an international investigation of the problem of influenza, in the hope of preventing these pandemics.

    eISBN: 978-0-8166-6155-8
    Subjects: Health Sciences

Table of Contents

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  1. Front Matter
    (pp. 1-4)
  2. Table of Contents
    (pp. 5-8)
    (pp. 9-14)
    Robert A. Good

    For more than a third of a century at the University of Minnesota, Wesley W. Spink—clinician, internist concerned with the broad realm of infectious disease in man, and experimental pathologist—has been directing his major energies to research on brucellosis. Driven certainly by the Oslerian concept “Know one disease completely and you know all of medicine,” Dr. Spink has contributed to the methods of diagnosis, the analysis of the pathogenetic mechanism, and the means of treatment and prevention of brucellosis. To achieve these goals, in different stages of inquiry he has had to be an anatomist, physiologist, pathologist, experimental...

    (pp. 15-18)
    W. I. B. Beveridge
    (pp. 19-20)

    Comparative medicine is one of the most exciting fields for scientific work. The horizons of scientists, like those of other men, tend to be restricted by the disciplines of their professional training, so that the weight of research carried out in medical and veterinary studies vastly exceeds that done in the common field. Nevertheless, the modest amount of comparative investigation carried out has already led to a body of discoveries which are fundamental and from which it is clear that the rewards of the comparative method are disproportionately greater than those of either of the two established separate disciplines. Ever...

    (pp. 21-40)

    Ordinarily we do not reason deliberately following the rules of logic, and we are not consciously aware of what makes our thoughts flow this way or that. I believe that the importance of the part played by analogy in our thinking—scientifically and otherwise—is not sufficiently appreciated. Very commonly our actions are the consequence of our regarding a new situation as analogous to one with which we are familiar.

    An analogy is a resemblance between the relationships of things, rather than between the things themselves. When one perceives that the relationship between A and B resembles the relationship between...

    (pp. 41-63)

    In the preceding chapter, I pointed out that the logic behind comparative medicine is that of doing research by analogy, and I outlined in general terms some of the fields in which this method has been successfully used. In this chapter, I shall look more closely at some model systems. First, however, I shall consider the ways in which suitable models for human problems are found.

    Basically, there are two approaches to the discovery of such models: starting from the animal or starting from man. In the first case, someone working with animals, usually a veterinarian, notices that an animal...

    (pp. 64-88)

    Influenza provides a splendid illustration of the unity of medicine on two grounds: the exchange of knowledge of the disease as it affects both man and animals and the exchange of infection between man and animals.

    That is my justification for making it the subject of this chapter, but I must admit that there is also another more personal reason. I am one of those who have been fascinated by the story that has unfolded over the last half century. The growth of our knowledge in this field constitutes one of the most exciting stories in the history of medicine...

    (pp. 89-92)
    (pp. 93-98)
  11. Index
    (pp. 99-104)